Mania possibly induced by clozapine: a case report
Nihan Oguz, Mustafa Gulec, Almila Erol
PDF
Article No: 10   Article Type :  Case Report
Manic shift can be caused by the use of atypical antipsychotics. Hypomanic/manic episodes caused by olanzapine, risperidone, quetiapine, ziprasidone, amisulpride, aripiprazole, zotepine, perospirone, and paliperidone have been frequently described in the literature. The proposed causes of mania/hypomania switching are due to blockages of 5HT2A and D2 receptors, enhancement of 5HT1A receptors, and dopamine release in the prefrontal/frontal regions. There have been no hypomanic/manic episodes described during clozapine use up to the present. A manic shift observed during clozapine use in a 30-year-old woman with schizoaffective disorder depressive type without any history of manic or mixed episodes was presented below.
Keywords : Atypical antipsychotic, clozapine, manic episode, schizoaffective disorder
Dusunen Adam The Journal of Psychiatry and Neurological Sciences 2014;27:348-351
SUBMIT AN ARTICLE
11th National Alcohol and Substance Abuse Congress
DUSUNEN ADAM BROCHURES
COVER
Creative Commons Lisansı

Dusunen Adam: The Journal of Psychiatry and Neurological Sciences is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi
Bakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim ve Araştırma Hastanesi
Yayıncı
Yerküre Tanıtım ve Yayıncılık Hizmetleri A.Ş.